CANIPEP | PEPTIDE EVIDENCE-READING WORKSHEET
Updated September 27, 2026

Discussion aid only. Not a clinical protocol or validated scoring instrument.
Full paper / DOI:
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1. Identify the material
Record the exact peptide, sequence or identifier, formulation and source reported by the authors. A familiar commercial name may describe something different.
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2. Identify the model
Was this a cell experiment, a rodent study, a study in dogs or work in people? Note the population and why it was selected.
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3. Name the actual question
Separate exposure, mechanism, tolerability and clinical benefit. State the question the experiment was designed to answer.
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4. Inspect the comparison
Record the control group, sample size, allocation and blinding where reported. Mark missing information as missing.
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5. Read the outcome carefully
What was measured, when, and for how long? Distinguish a laboratory marker from an outcome that matters to a dog and its veterinarian.
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6. Keep uncertainty visible
Record variability, limitations and adverse findings alongside the positive findings. Note what was not measured or reported.
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7. Check the translation
Do the species, formulation and setting match the proposed question? Write down every step that would need further evidence.
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8. Separate the product questions
List the identity, manufacturing, stability, compatibility and regulatory questions that the paper does not answer.
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9. Look for independent support
Search for replication, contradictory results, corrections and retractions. Record funding and conflicts disclosed by the authors.
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10. Write a bounded conclusion
Complete: “This study supports ___ in ___ under ___ conditions. It does not establish ___.” Keep the conclusion no broader than the experiment.
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Source context: https://canipep.com/resources/peptide-evidence-checklist/
More sources: https://canipep.com/science/
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